NAD+ (Nicotinamide Adenine Dinucleotide)
Oxidized pyridine dinucleotide coenzyme central to redox biochemistry, sirtuin signaling, and metabolic pathway research models.
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Longevity & Cellular
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MOTS-c
Mitochondrial-derived signaling peptide
≥98% HPLC
MS Identity
COA included
$80
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For research use only — not for human or veterinary use
Ships with a lot-specific Certificate of Analysis
Lyophilized & cold-chain handled for stability
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Overview
MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded within the mitochondrial MT-RNR1 locus, making it a member of the mitochondrial-derived peptide (MDP) class. This catalog item is supplied as a high-purity synthetic analog (sequence MRWQEMGYIFYPRKLR) for in vitro and biochemical investigation. It is provided strictly for laboratory research use only and is not intended for human or veterinary use.
In published literature, MOTS-c has been studied as a regulator of cellular energy sensing, with reported associations to AMP-activated protein kinase (AMPK) activation, glucose flux, and the folate-methionine metabolic axis. It has also been examined for nuclear translocation under metabolic stress and interaction with casein kinase 2. Researchers use the peptide as a tool compound in cell-based assays and mitochondrial biology models.
Research areas
- Mitochondrial-derived peptide biology
- AMPK and cellular energy-sensing pathways
- Glucose and lipid metabolism signaling models
- Cellular stress and nuclear translocation studies
- Longevity and cellular senescence research
- Skeletal muscle metabolism models
Handling & storage
Store lyophilized powder at -20 C protected from light and moisture; stable for extended periods. Reconstituted solutions should be stored at -20 C or below in aliquots to avoid repeated freeze-thaw cycles.
For laboratory research use only. Reconstitute in sterile water or bacteriostatic water; the peptide is soluble in aqueous buffer. Not for human or veterinary use.
Specifications
FormLyophilized powder
Purity>=98% (HPLC)
SequenceMRWQEMGYIFYPRKLR
Molecular formulaC101H152N28O22S2
Molecular weight2174.6 g/mol
CAS number1627580-64-6
SynonymsMitochondrial-derived peptide MOTS-c, MOTSc, MT-RNR1 peptide, Mitochondrial ORF of the 12S rRNA type-c
Certificate of Analysis
Each lot ships with documentation confirming purity (HPLC) and identity (MS).
View sample COACompliance: Sold to qualified researchers for laboratory use only. Lot COA reflects the authoritative values for your specific shipment.
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