MOTS-c — Certificate of Analysis

Lot MS10-2026-001 of MOTS-c assayed at 99.79% peptide purity by RP-HPLC against a ≥95.0% release specification, 4.79 percentage points clear of it. Released 07/15/2026 by ILS Laboratories, ISO/IEC 17025 Accredited. Synthetic 16-residue mitochondrial-derived peptide (MT-RNR1) used in research on AMPK signaling and cellular metabolic homeostasis.

Net peptide content measured 10.24 mg against a 10 mg label — the mass of actual peptide in the vial, as distinct from salts, water and counter-ions. It is reported rather than graded, so it carries no pass/fail.

Full QC panel

Analyte	Specification	Result	Status
Peptide Purity (HPLC)	≥ 95.0%	99.79%	Pass
Identity (HPLC-RTM)	MOTS-c Confirmed	Confirmed	Pass
Net Peptide Content	Report Only	10.24 mg	—
Fentanyl Screen	Immunoassay, 50 ng/mL cutoff	Not Detected	Pass

Sterility & endotoxin

Test	Specification	Result	Status
Sterility (PCR)	No Growth	No Growth	Pass
Endotoxin (USP <85>)	Report Result	NMT 0.05 EU/mL	Reported

Endotoxin is reported as a measured value rather than graded pass/fail: acceptable limits depend on route and matrix, and no universal threshold applies to research-use material. The laboratory reports the figure and leaves the judgement to you.

Elemental impurities

Panel	Method	Result	Status
Arsenic, cadmium, chromium, lead, mercury	ICP-MS, USP <233>	5 of 5 under limit	Pass

Per-element measurements are on the signed certificate below.

Reference data

Property	Value
Compound	MOTS-c
Also known as	Mitochondrial-derived peptide MOTS-c, MOTSc, MT-RNR1 peptide, Mitochondrial ORF of the 12S rRNA type-c
Sequence	MRWQEMGYIFYPRKLR
Molecular formula	C101H152N28O22S2
Molecular weight	2174.6 g/mol
CAS number	1627580-64-6
Physical form	Lyophilized powder
Storage	Store lyophilized powder at -20 C protected from light and moisture; stable for extended periods. Reconstituted solutions should be stored at -20 C or below in aliquots to avoid repeated freeze-thaw cycles.