Selank

Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from the endogenous immunomodulatory tetrapeptide tuftsin, extended at the C-terminus with a Pro-Gly-Pro tripeptide. This structural modification was designed to confer greater resistance to enzymatic degradation and improved metabolic stability relative to the parent sequence. The compound was originally developed at the Institute of Molecular Genetics of the Russian Academy of Sciences and is widely referenced in the peptide neuroscience literature.

In experimental systems, Selank has been investigated for its interactions with GABAergic, serotonergic, dopaminergic, and enkephalin-related signaling, as well as its reported modulation of brain-derived neurotrophic factor expression. It serves as a reference tool compound in research examining anxiolytic mechanisms, nootropic activity, and neuro-immune crosstalk. This material is supplied strictly for in vitro and laboratory research applications and is not intended for human or veterinary use.

Store lyophilized powder at -20C protected from light and moisture for long-term stability. After reconstitution, store at 2-8C and use within a short period; avoid repeated freeze-thaw cycles.

For research applications, reconstitute in sterile bacteriostatic or distilled water; gently swirl rather than shake to preserve peptide integrity.