GHK-Cu

GHK-Cu (copper tripeptide-1) is the copper(II) coordination complex of the naturally occurring tripeptide glycyl-L-histidyl-L-lysine (GHK). The histidine imidazole and backbone nitrogen atoms chelate a single Cu(II) ion, yielding a defined metallopeptide that serves as a reference reagent for studies of copper transport, peptide-metal coordination chemistry, and extracellular matrix signaling in cell-culture systems.

In laboratory settings, GHK-Cu is widely used as a tool compound for investigating fibroblast behavior, collagen and glycosaminoglycan biosynthesis, and copper-dependent enzymatic pathways in vitro. It is provided strictly as a research material for use in cell-based assays, biochemical characterization, and analytical method development. This product is for laboratory research use only and is not intended for human or veterinary use.

Store lyophilized powder at -20C protected from light and moisture; stable for up to 24 months. Aliquot reconstituted solutions and store at -20C to avoid repeated freeze-thaw cycles.

Reconstitute in sterile deionized water or PBS; protect working solutions from prolonged light exposure and avoid strong chelators that may displace the bound copper.